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Thioketal formation by substrate pyruvate and Cys residue in the enzyme. The formation of this thioketal transforms the enzyme from its inactive to its active state.

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Thioketal

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[edit] Reference

Lobell, Mario and David H.G. Crout Pyruvate decarboxylase: a molecular modeling study of pyruvate decarboxylation and acyloin formation Journal of American Chemistry Society 1996: 118(8) 1867-1873

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current00:23, 7 December 2007500×151 (3 KB)Cwernert (Talk | contribs) (Thioketal)

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