Itaconyl-CoA hydratase

From Wikipedia, the free encyclopedia

In enzymology, an itaconyl-CoA hydratase (EC 4.2.1.56) is an enzyme that catalyzes the chemical reaction

citramalyl-CoA itaconyl-CoA + H₂O

Hence, this enzyme has one substrate, citramalyl-CoA, and two products, itaconyl-CoA and H₂O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is citramalyl-CoA hydro-lyase (itaconyl-CoA-forming). Other names in common use include itaconyl coenzyme A hydratase, and citramalyl-CoA hydro-lyase. This enzyme participates in c5-branched dibasic acid metabolism.

[edit] References

• IUBMB entry for 4.2.1.56
• BRENDA references for 4.2.1.56 (Recommended.)
• PubMed references for 4.2.1.56
• PubMed Central references for 4.2.1.56
• Google Scholar references for 4.2.1.56
• Cooper RA, Kornberg HL (1964). "The utilization of itaconate by Pseudomonas sp". Biochem. J. 91: 82–91. PMID 4284209. 

[edit] External links

The CAS registry number for this enzyme class is 37290-83-8.

• IUBMB entry for 4.2.1.56

• KEGG entry for 4.2.1.56

• BRENDA entry for 4.2.1.56

• NiceZyme view of 4.2.1.56

• EC2PDB: PDB structures for 4.2.1.56

• PRIAM entry for 4.2.1.56

• PUMA2 entry for 4.2.1.56

• IntEnz: Integrated Enzyme entry for 4.2.1.56

• MetaCyc entry for 4.2.1.56

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050011: itaconyl-CoA hydratase

• AMIGO entry for GO code 0050011: itaconyl-CoA hydratase