Isovaleramide
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Isovaleramide | |
---|---|
Other names | 3-Methylbutyramide Isopentanamide Isovaleric acid amide Isovaleric amide beta-Methylbutyramide |
Properties | |
Molecular formula | C5H11NO |
Molar mass | 101.15 |
Melting point |
137 °C |
Boiling point |
226 °C |
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
Isovaleramide is an amide found in Valerian root. In humans, it acts as a mild anxiolytic at lower doses and as a mild sedative at higher dosages. Isovaleramide has been shown to be non-cytotoxic and does not act as a CNS stimulant. It inhibits the liver alcohol dehydrogenases and has a reported LD50 of greater than 400 mg/kg when administered intraperitoneally in mice.[1]
[edit] References
- ^ "{{{title}}}" (1975). European Journal of Medicinal Chemistry 10: 453.