Isomaltulose synthase

From Wikipedia, the free encyclopedia

In enzymology, an isomaltulose synthase (EC 5.4.99.11) is an enzyme that catalyzes the chemical reaction

sucrose $\rightleftharpoons$ 6-O-alpha-D-glucopyranosyl-D-fructofuranose

Hence, this enzyme has one substrate, sucrose, and one product, 6-O-alpha-D-glucopyranosyl-D-fructofuranose.

This enzyme belongs to the family of isomerases, specifically those intramolecular transferases transferring other groups. The systematic name of this enzyme class is sucrose glucosylmutase. Other names in common use include isomaltulose synthetase, sucrose alpha-glucosyltransferase, and trehalulose synthase.

1 Structural studies
2 References
3 External links
- 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1M53, 1ZJA, 1ZJB, 2PWD, 2PWE, 2PWF, and 2PWG.

[edit] References

IUBMB entry for 5.4.99.11
BRENDA references for 5.4.99.11 (Recommended.)
PubMed references for 5.4.99.11
PubMed Central references for 5.4.99.11
Google Scholar references for 5.4.99.11
Cheetham PS (1984). "The extraction and mechanism of a novel isomaltulose-synthesizing enzyme from Erwinia rhapontici". Biochem. J. 220: 213–20. PMID 6743261.
Cheetham PSJ, Imber CE and Isherwood J (1982). "The formation of isomaltulose by immobilized Erwinia rhapontici". Nature 299: 628–631. doi:10.1038/299628a0.