Isofuran

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Isofurans are nonclassic eicosanoids formed nonenzymatically by free radical mediated peroxidation of arachidonic acid. The isofurans are similar to the isoprostanes and are formed under similar conditions, but contain a substituted tetrahydrofuran ring. The concentration of oxygen affects this process; at elevated oxygen concentrations, the formation of isofurans is favored whereas the formation of isoprostanes is disfavored.[1]

[edit] References

  1. ^ Roberts, LJ 2nd and Fessel, JP (2004 Mar). "The biochemistry of the isoprostane, neuroprostane, and isofuran pathways of lipid peroxidation.". Chem Phys Lipids 128 ((1-2)): 173–86.. doi:10.1111/j.1750-3639.2005.tb00511.x.  PMID: 15037162
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