Isabella Clark
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Credit: Library and Archives Canada, Acc. No. 1960-123-3
Isabella Clark (1811–1857) was the first wife of John A. Macdonald, the premier of the Province of Canada in 1856 (after Clark's death he went on to become the first post-Confederation Prime Minister of Canada). She was his first cousin. She became ill after just two years marriage in 1845 and died. Medical examinations concluded that she was suffering from a somatization disease. They had two sons: John and Hugh; the former died at 13 months. She had also developed an addiction to opium mixed with wine.
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