IPEX
From Wikipedia, the free encyclopedia
| IPEX Classification and external resources |
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| OMIM | 304790 |
|---|---|
| DiseasesDB | 33417 |
IPEX stands for immunodysregulation polyendocrinopathy enteropathy X-linked syndrome and it is a rare disease linked to the dysfunction of the transcriptional activator FoxP3.
It leads to the dysfunction of regulatory T-cells and the subsequent autoimmunity.
This autoimmunity is called IPEX and it is the attack from the body's own immune system against the body's own tissues and organs. Early age onset of this disease in males causes severe enlargement of the secondary lymphoid organs, insulin dependent diabetes, eczema, food allergies, and infections. There is no treatment and the condition is fatal.
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[edit] See also
- Autoimmune polyendocrine syndrome
- IPEX Also stands for (Investment Platform of Entrepreneurship eXchange) (پایگاه سرمایه گذاری بورس کارآفرینی . http://www.ipex.ir . an iranian platform of entrepreneurship)
