Inulin fructotransferase (DFA-III-forming)

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In enzymology, an inulin fructotransferase (DFA-III-forming) (EC 4.2.2.18) is an enzyme that catalyzes the chemical reaction

Produces alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride (DFA III) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is 2,1-beta-D-fructan lyase (alpha-D-fructofuranose-beta-D-fructofuranose-1,2':2,3'-dianhydride- forming). Other names in common use include inulin fructotransferase (DFA-III-producing), inulin fructotransferase (depolymerizing), inulase II, inulinase II, inulin fructotransferase (depolymerizing,, difructofuranose-1,2':2,3'-dianhydride-forming), inulin D-fructosyl-D-fructosyltransferase, (1,2':2,3'-dianhydride-forming), inulin D-fructosyl-D-fructosyltransferase (forming, and alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride).

[edit] Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2INU and 2INV.

[edit] References

IUBMB entry for 4.2.2.18
BRENDA references for 4.2.2.18 (Recommended.)
PubMed references for 4.2.2.18
PubMed Central references for 4.2.2.18
Google Scholar references for 4.2.2.18
Uchiyama T (1975). "Action of Arthrobacter ureafaciens inulinase II on several oligofructans and bacterial levans". Biochim. Biophys. Acta. 397: 153–63. PMID 1148257.
Uchiyama T, Niwa S and Tanaka K (1973). "Purification and properties of Arthrobacter ureafaciens inulase II". Biochim. Biophys. Acta 315: 412–420.