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The internal urethral orifice is the opening of the urinary bladder into the urethra. It is placed at the apex of the trigonum vesicae, in the most dependent part of the bladder, and is usually somewhat crescent-shaped; the mucous membrane immediately behind it presents a slight elevation in males, the uvula vesicae, caused by the middle lobe of the prostate.
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This article was originally based on an entry from a public domain edition of Gray's Anatomy. As such, some of the information contained herein may be outdated. Please edit the article if this is the case, and feel free to remove this notice when it is no longer relevant.