From Wikipedia, the free encyclopedia
Interleukin-28 receptor is a type II cytokine receptor. It binds interleukin-28. It consists of an α and shares a common β subunit the with interleukin-10 receptor.[1][2]
[edit] References
- ^ Kotenko SV, Gallagher G, Baurin VV, Lewis-Antes A, Shen M, Shah NK, Langer JA, Sheikh F, Dickensheets H, Donnelly RP (2003). "IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex". Nat. Immunol. 4 (1): 69–77. doi:10.1038/ni875. PMID 12483210.
- ^ Sheppard P, Kindsvogel W, Xu W, Henderson K, Schlutsmeyer S, Whitmore TE, Kuestner R, Garrigues U, Birks C, Roraback J, Ostrander C, Dong D, Shin J, Presnell S, Fox B, Haldeman B, Cooper E, Taft D, Gilbert T, Grant FJ, Tackett M, Krivan W, McKnight G, Clegg C, Foster D, Klucher KM (2003). "IL-28, IL-29 and their class II cytokine receptor IL-28R". Nat. Immunol. 4 (1): 63–8. doi:10.1038/ni873. PMID 12469119.
[edit] External links
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Transmembrane receptors: immune receptors |
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| Cytokine receptor |
Type I: Interleukins ( 2, 3, 4, 5, 6, 7, 9, 11, 12, 13, 15, 21, 23, 27), CSF receptors ( EPO, GM-CSF, G-CSF), GH, prolactin, Oncostatin M, Leukemia inhibitory factor - common subunits ( Common gamma chain, common beta chain, CSF2RB)
Type II: Interleukins (10, 20, 22, 28) - interferon (-α/β, -γ)
immunoglobulin superfamily: CSF1, C-kit, IL-1, IL-18
Tumor necrosis factor: CD27, CD30, CD40, CD120, Lymphotoxin β
Chemokines: IL-8 (α, β), CCR1,CXCR4
Other: IL-17, TGF-beta ( 1, 2)
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| Pattern recognition/Toll-like |
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| Fc receptor |
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| Lymphocyte homing receptor |
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| other |
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