Insertional inactivation

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Insertional inactivation is a technique used in recombinant DNA engineering where a plasmid (such as pBR322)[1] is used to disable expression of a gene.[2]

The inactivation of a gene by inserting a fragment of DNA into the middle of its coding sequence. Any future products from the inactivated gene will not work because of the extra codes added to it.


[edit] References

  1. ^ Recombinant DNA
  2. ^ Insertional inactivation

[edit] External links

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