INSL5

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Insulin-like 5
Identifiers
Symbol(s) INSL5; MGC126695; MGC126697; PRO182; UNQ156
External IDs OMIM: 606413 MGI: 1346085 HomoloGene: 48350
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 10022 23919
Ensembl ENSG00000172410 ENSMUSG00000066090
Uniprot Q9Y5Q6 Q9WUG6
Refseq NM_005478 (mRNA)
NP_005469 (protein)		 NM_011831 (mRNA)
NP_035961 (protein)
Location Chr 1: 67.04 - 67.04 Mb Chr 4: 102.52 - 102.52 Mb
Pubmed search [1] [2]

Insulin-like 5, also known as INSL5, is a human gene.[1]

The protein encoded by this gene contains a classical signature of the insulin superfamily and is highly similar to relaxin 3 (RLN3/INSL7).[1]

[edit] References

  1. ^ a b Entrez Gene: INSL5 insulin-like 5.

[edit] Further reading

  • Liu C, Kuei C, Sutton S, et al. (2005). "INSL5 is a high affinity specific agonist for GPCR142 (GPR100).". J. Biol. Chem. 280 (1): 292-300. doi:10.1074/jbc.M409916200. PMID 15525639. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites.". Protein Sci. 13 (10): 2819-24. doi:10.1110/ps.04682504. PMID 15340161. 
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi:10.1101/gr.1293003. PMID 12975309. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Conklin D, Lofton-Day CE, Haldeman BA, et al. (1999). "Identification of INSL5, a new member of the insulin superfamily.". Genomics 60 (1): 50-6. doi:10.1006/geno.1999.5899. PMID 10458910. 
  • Koman A, Cazaubon S, Couraud PO, et al. (1996). "Molecular characterization and in vitro biological activity of placentin, a new member of the insulin gene family.". J. Biol. Chem. 271 (34): 20238-41. PMID 8702754. 
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