Inositol 3-alpha-galactosyltransferase

From Wikipedia, the free encyclopedia

In enzymology, an inositol 3-alpha-galactosyltransferase (EC 2.4.1.123) is an enzyme that catalyzes the chemical reaction

UDP-galactose + myo-inositol UDP + O-alpha-D-galactosyl-(1->3)-1D-myo-inositol

Thus, the two substrates of this enzyme are UDP-galactose and myo-inositol, whereas its two products are UDP and [[O-alpha-D-galactosyl-(1->3)-1D-myo-inositol]].

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:myo-inositol 3-alpha-D-galactosyltransferase. Other names in common use include UDP-D-galactose:inositol galactosyltransferase, UDP-galactose:myo-inositol 1-alpha-D-galactosyltransferase, UDPgalactose:myo-inositol 1-alpha-D-galactosyltransferase, galactinol synthase, inositol 1-alpha-galactosyltransferase, and uridine diphosphogalactose-inositol galactosyltransferase. This enzyme participates in galactose metabolism.

[edit] References

• IUBMB entry for 2.4.1.123
• BRENDA references for 2.4.1.123 (Recommended.)
• PubMed references for 2.4.1.123
• PubMed Central references for 2.4.1.123
• Google Scholar references for 2.4.1.123
• Pharr DM, Sox, HN, Locy RD and Huber SC (1981). "Partial characterization of the galactinol forming enzyme from leaves of Cucumis sativus L". Plant Sci. Lett. 23: 25–33. 

[edit] External links

The CAS registry number for this enzyme class is 79955-89-8.

• IUBMB entry for 2.4.1.123

• KEGG entry for 2.4.1.123

• BRENDA entry for 2.4.1.123

• NiceZyme view of 2.4.1.123

• EC2PDB: PDB structures for 2.4.1.123

• PRIAM entry for 2.4.1.123

• PUMA2 entry for 2.4.1.123

• IntEnz: Integrated Enzyme entry for 2.4.1.123

• MetaCyc entry for 2.4.1.123

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047216: inositol 3-alpha-galactosyltransferase

• AMIGO entry for GO code 0047216: inositol 3-alpha-galactosyltransferase