Inosine kinase

From Wikipedia, the free encyclopedia

In enzymology, an inosine kinase (EC 2.7.1.73) is an enzyme that catalyzes the chemical reaction

ATP + inosine ADP + IMP

Thus, the two substrates of this enzyme are ATP and inosine, whereas its two products are ADP and IMP.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:inosine 5'-phosphotransferase. Other names in common use include inosine-guanosine kinase, and inosine kinase (phosphorylating). This enzyme participates in purine metabolism.

[edit] References

• IUBMB entry for 2.7.1.73
• BRENDA references for 2.7.1.73 (Recommended.)
• PubMed references for 2.7.1.73
• PubMed Central references for 2.7.1.73
• Google Scholar references for 2.7.1.73
• Pierre KJ, LePage GA (1968). "Formation of inosine-5'-monophosphate by a kinase in cell-free extracts of Ehrlich ascites cells in vitro". Proc. Soc. Exp. Biol. Med. 127: 432–40. PMID 5645030. 

[edit] External links

The CAS registry number for this enzyme class is 37237-46-0.

• IUBMB entry for 2.7.1.73

• KEGG entry for 2.7.1.73

• BRENDA entry for 2.7.1.73

• NiceZyme view of 2.7.1.73

• EC2PDB: PDB structures for 2.7.1.73

• PRIAM entry for 2.7.1.73

• PUMA2 entry for 2.7.1.73

• IntEnz: Integrated Enzyme entry for 2.7.1.73

• MetaCyc entry for 2.7.1.73

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0008906: inosine kinase

• AMIGO entry for GO code 0008906: inosine kinase