Inosinate nucleosidase

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In enzymology, an inosinate nucleosidase (EC 3.2.2.12) is an enzyme that catalyzes the chemical reaction

5'-inosinate + H₂O D-ribose 5-phosphate + hypoxanthine

Thus, the two substrates of this enzyme are 5'-inosinate and H₂O, whereas its two products are D-ribose 5-phosphate and hypoxanthine.

This enzyme belongs to the family of hydrolases, specifically those glycosylases that hydrolyse N-glycosyl compounds. The systematic name of this enzyme class is 5'-inosinate phosphoribohydrolase. This enzyme participates in purine metabolism.

[edit] References

• IUBMB entry for 3.2.2.12
• BRENDA references for 3.2.2.12 (Recommended.)
• PubMed references for 3.2.2.12
• PubMed Central references for 3.2.2.12
• Google Scholar references for 3.2.2.12
• Kuninaka A (1957). "5'-Inosinic acid-N-ribosidase in Aspergillus". Koso Kagaka Shinojiumu 12: 65–69. 

[edit] External links

The CAS registry number for this enzyme class is 37288-61-2.

• IUBMB entry for 3.2.2.12

• KEGG entry for 3.2.2.12

• BRENDA entry for 3.2.2.12

• NiceZyme view of 3.2.2.12

• EC2PDB: PDB structures for 3.2.2.12

• PRIAM entry for 3.2.2.12

• PUMA2 entry for 3.2.2.12

• IntEnz: Integrated Enzyme entry for 3.2.2.12

• MetaCyc entry for 3.2.2.12

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047723: inosinate nucleosidase

• AMIGO entry for GO code 0047723: inosinate nucleosidase