Inorganic pyrophosphatase

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pyrophosphatase (inorganic) 1
Identifiers
Symbol PPA1
Alt. Symbols PP
Entrez 5464
HUGO 9226
OMIM 179030
RefSeq NM_021129
UniProt Q15181
Other data
EC number 3.6.1.1
Locus Chr. 10 q11.1-q24
pyrophosphatase (inorganic) 2
Identifiers
Symbol PPA2
Entrez 27068
HUGO 28883
OMIM 609988
RefSeq NM_176869
UniProt Q9H2U2
Other data
Locus Chr. 4 q25

Pyrophosphatase (or inorganic pyrophosphatase) is an enzyme that converts one molecule of pyrophosphate to two phosphate ions. This highly exergonic reaction (about -34KJ change in free energy) can be coupled to unfavorable biochemical transformations in order to drive these transformations to completion, as in Lipid synthesis and other biochemical transformations.

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