Indole-3-acetaldehyde oxidase

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In enzymology, an indole-3-acetaldehyde oxidase (EC 1.2.3.7) is an enzyme that catalyzes the chemical reaction

(indol-3-yl)acetaldehyde + H₂O + O₂ $\rightleftharpoons$ (indol-3-yl)acetate + H₂O₂

The 3 substrates of this enzyme are (indol-3-yl)acetaldehyde, H₂O, and O₂, whereas its two products are (indol-3-yl)acetate and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with oxygen as acceptor. The systematic name of this enzyme class is (indol-3-yl)acetaldehyde:oxygen oxidoreductase. Other names in common use include indoleacetaldehyde oxidase, IAAld oxidase, AO1, and indole-3-acetaldehyde:oxygen oxidoreductase. This enzyme participates in tryptophan metabolism. It has 3 cofactors: FAD, Heme, and Molybdenum.

[edit] References

IUBMB entry for 1.2.3.7
BRENDA references for 1.2.3.7 (Recommended.)
PubMed references for 1.2.3.7
PubMed Central references for 1.2.3.7
Google Scholar references for 1.2.3.7
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