Image:Importin complex.jpg

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[edit] Summary

Description

Importin complex

The importin complex shown here (built from three separate PDB entries) transports proteins with nuclear localization signals. At the top in blue is importin-beta (PDB entry 1qgk). It is the engine of the complex, recognizing nuclear pores and moving through them. It wraps around the end of importin-alpha, shown at the center in green (1ee5). Importin-alpha is an adapter molecule that connects importin-beta with the cargo. In this picture, the cargo is nucleoplasmin, shown at the bottom in yellow (1k5j), a chaperone protein that is important in nucleosome assembly. (more details...)

Source

Molecule of the Month by www.pdb.org (see the Molecule of the Month section for more details)

Date

Year 2007 (see the complete list for more details)

Author

Illustration by David S. Goodsell of The Scripps Research Institute (see this site)

Permission
(Reusing this image)

Original work of the US Federal Government - public domain


[edit] Licensing

Public domain This work is in the public domain in the United States because it is a work of the United States Federal Government under the terms of Title 17, Chapter 1, Section 105 of the US Code. See Copyright.

Note: This only applies to works of the Federal Government and not to the work of any individual U.S. state, territory, commonwealth, county, municipality, or any other subdivision.


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current21:19, 8 January 2007348×700 (117 KB)Patho ({{Information| |Description=Importin complex The importin complex shown here (built from three separate PDB entries) transports proteins with nuclear localization signals. At the top in blue is importin-beta (PDB entry 1qgk). It is the engine of the comp)
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