IMPG1

From Wikipedia, the free encyclopedia

Interphotoreceptor matrix proteoglycan 1

Identifiers

IMPG1; GP147; IPM150; SPACR

External IDs

OMIM: 602870 MGI: 1926876 HomoloGene: 1201

Gene ontology
Molecular Function:	• receptor activity • extracellular matrix structural constituent
Cellular Component:	• proteinaceous extracellular matrix
Biological Process:	• visual perception

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_001563 (mRNA)
NP_001554 (protein)

XM_986383 (mRNA)
XP_991477 (protein)

Location

Chr 6: 76.69 - 76.84 Mb

Chr 9: 80.1 - 80.19 Mb

Pubmed search

[1]

[2]

Interphotoreceptor matrix proteoglycan 1, also known as IMPG1, is a human gene.^[1]

[edit] References

^ Entrez Gene: IMPG1 interphotoreceptor matrix proteoglycan 1.

[edit] Further reading

Felbor U, Gehrig A, Sauer CG, et al. (1998). "Genomic organization and chromosomal localization of the interphotoreceptor matrix proteoglycan-1 (IMPG1) gene: a candidate for 6q-linked retinopathies.". Cytogenet. Cell Genet. 81 (1): 12–7. PMID 9691169.
Gehrig A, Felbor U, Kelsell RE, et al. (1998). "Assessment of the interphotoreceptor matrix proteoglycan-1 (IMPG1) gene localised to 6q13-q15 in autosomal dominant Stargardt-like disease (ADSTGD), progressive bifocal chorioretinal atrophy (PBCRA), and North Carolina macular dystrophy (MCDR1).". J. Med. Genet. 35 (8): 641–5. PMID 9719369.
Acharya S, Rayborn ME, Hollyfield JG (1998). "Characterization of SPACR, a sialoprotein associated with cones and rods present in the interphotoreceptor matrix of the human retina: immunological and lectin binding analysis.". Glycobiology 8 (10): 997–1006. PMID 9719680.
Acharya S, Rodriguez IR, Moreira EF, et al. (1998). "SPACR, a novel interphotoreceptor matrix glycoprotein in human retina that interacts with hyaluronan.". J. Biol. Chem. 273 (47): 31599–606. PMID 9813076.
Kuehn MH, Hageman GS (2000). "Expression and characterization of the IPM 150 gene (IMPG1) product, a novel human photoreceptor cell-associated chondroitin-sulfate proteoglycan.". Matrix Biol. 18 (5): 509–18. PMID 10601738.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
van Lith-Verhoeven JJ, Hoyng CB, van den Helm B, et al. (2004). "The benign concentric annular macular dystrophy locus maps to 6p12.3-q16.". Invest. Ophthalmol. Vis. Sci. 45 (1): 30–5. PMID 14691150.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Abd El-Aziz MM, El-Ashry MF, Barragan I, et al. (2006). "Molecular genetic analysis of two functional candidate genes in the autosomal recessive retinitis pigmentosa, RP25, locus.". Curr. Eye Res. 30 (12): 1081–7. doi:10.1080/02713680500351039. PMID 16354621.