IL17RC

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Interleukin 17 receptor C
Identifiers
Symbol(s) IL17RC; IL17-RL; MGC10763
External IDs MGI: 2159336 HomoloGene: 15894
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 84818 171095
Ensembl ENSG00000163702 ENSMUSG00000030281
Uniprot Q8NAC3 Q8BPI5
Refseq NM_032732 (mRNA)
NP_116121 (protein)		 NM_134159 (mRNA)
NP_598920 (protein)
Location Chr 3: 9.93 - 9.95 Mb Chr 6: 113.44 - 113.45 Mb
Pubmed search [1] [2]

Interleukin 17 receptor C, also known as IL17RC, is a human gene.[1]

This gene encodes a single-pass transmembrane protein that shares limited similarity with the interleukin-17 receptor. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only three have been determined to date.[1]

Contents

[edit] See also

[edit] References

  1. ^ a b Entrez Gene: IL17RC interleukin 17 receptor C.

[edit] Further reading

  • Gerritsen ME, Tomlinson JE, Zlot C, et al. (2004). "Using gene expression profiling to identify the molecular basis of the synergistic actions of hepatocyte growth factor and vascular endothelial growth factor in human endothelial cells.". Br. J. Pharmacol. 140 (4): 595–610. doi:10.1038/sj.bjp.0705494. PMID 14504135. 
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149. 
  • Haudenschild D, Moseley T, Rose L, Reddi AH (2002). "Soluble and transmembrane isoforms of novel interleukin-17 receptor-like protein by RNA splicing and expression in prostate cancer.". J. Biol. Chem. 277 (6): 4309–16. doi:10.1074/jbc.M109372200. PMID 11706037. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites.". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMID 15340161. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Haudenschild DR, Curtiss SB, Moseley TA, Reddi AH (2006). "Generation of interleukin-17 receptor-like protein (IL-17RL) in prostate by alternative splicing of RNA.". Prostate 66 (12): 1268–74. doi:10.1002/pros.20422. PMID 16688746. 
  • Toy D, Kugler D, Wolfson M, et al. (2006). "Cutting edge: interleukin 17 signals through a heteromeric receptor complex.". J. Immunol. 177 (1): 36–9. PMID 16785495. 
  • Kuestner RE, Taft DW, Haran A, et al. (2007). "Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F.". J. Immunol. 179 (8): 5462–73. PMID 17911633. 

[edit] External links

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.