IGJ

From Wikipedia, the free encyclopedia


Immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
Identifiers
Symbol(s) IGJ; IGCJ; JCH
External IDs OMIM: 147790 MGI: 96493 HomoloGene: 16958
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 3512 16069
Ensembl ENSG00000132465 ENSMUSG00000067149
Uniprot P01591 P01592
Refseq NM_144646 (mRNA)
NP_653247 (protein)		 NM_152839 (mRNA)
NP_690052 (protein)
Location Chr 4: 71.74 - 71.75 Mb Chr 5: 89.6 - 89.6 Mb
Pubmed search [1] [2]

Immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides, also known as IGJ, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: IGJ immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides.

[edit] Further reading

  • Koshland ME (1986). "The coming of age of the immunoglobulin J chain.". Annu. Rev. Immunol. 3: 425-53. doi:10.1146/annurev.iy.03.040185.002233. PMID 2415140. 
  • Tartakoff A, Vassalli P (1980). "Plasma cell immunoglobulin M molecules. Their biosynthesis, assembly, and intracellular transport.". J. Cell Biol. 83 (2 Pt 1): 284-99. PMID 115892. 
  • Mole JE, Bhown AS, Bennett JC (1977). "Primary structure of human J chain: alignment of peptides from chemical and enzymatic hydrolyses.". Biochemistry 16 (16): 3507-13. PMID 407930. 
  • Bastian A, Kratzin H, Eckart K, Hilschmann N (1993). "Intra- and interchain disulfide bridges of the human J chain in secretory immunoglobulin A.". Biol. Chem. Hoppe-Seyler 373 (12): 1255-63. PMID 1292512. 
  • Frutiger S, Hughes GJ, Paquet N, et al. (1993). "Disulfide bond assignment in human J chain and its covalent pairing with immunoglobulin M.". Biochemistry 31 (50): 12643-7. PMID 1472500. 
  • Moro I, Iwase T, Komiyama K, et al. (1990). "Immunoglobulin A (IgA) polymerization sites in human immunocytes: immunoelectron microscopic study.". Cell Struct. Funct. 15 (2): 85-91. PMID 2113434. 
  • Alberini CM, Bet P, Milstein C, Sitia R (1990). "Secretion of immunoglobulin M assembly intermediates in the presence of reducing agents.". Nature 347 (6292): 485-7. doi:10.1038/347485a0. PMID 2120591. 
  • Max EE, Korsmeyer SJ (1985). "Human J chain gene. Structure and expression in B lymphoid cells.". J. Exp. Med. 161 (4): 832-49. PMID 2984306. 
  • Max EE, McBride OW, Morton CC, Robinson MA (1986). "Human J chain gene: chromosomal localization and associated restriction fragment length polymorphisms.". Proc. Natl. Acad. Sci. U.S.A. 83 (15): 5592-6. PMID 3016707. 
  • Sumi Y, Nagura H, Kaneda T, Oka T (1989). "Immunoelectron microscopical localization of immunoglobulins, secretory component and J chain in the human minor salivary glands.". J. Oral Pathol. 17 (8): 390-5. PMID 3146624. 
  • Hajdu I, Moldoveanu Z, Cooper MD, Mestecky J (1984). "Ultrastructural studies of human lymphoid cells. mu and J chain expression as a function of B cell differentiation.". J. Exp. Med. 158 (6): 1993-2006. PMID 6417260. 
  • Yasuda N, Kanoh T, Uchino H (1980). "J chain synthesis in human myeloma cells: light and electron microscopic studies.". Clin. Exp. Immunol. 40 (3): 573-80. PMID 6774844. 
  • Harper SJ, Allen AC, Béné MC, et al. (1995). "Increased dimeric IgA-producing B cells in tonsils in IgA nephropathy determined by in situ hybridization for J chain mRNA.". Clin. Exp. Immunol. 101 (3): 442-8. PMID 7664491. 
  • Iwase T, Saito I, Takahashi T, et al. (1994). "Early expression of human J chain and mu chain gene in the fetal liver.". Cell Struct. Funct. 18 (5): 297-302. PMID 8168154. 
  • Harper SJ, Pringle JH, Wicks AC, et al. (1994). "Expression of J chain mRNA in duodenal IgA plasma cells in IgA nephropathy.". Kidney Int. 45 (3): 836-44. PMID 8196286. 
  • Bjercke S, Brandtzaeg P (1994). "Glandular distribution of immunoglobulins, J chain, secretory component, and HLA-DR in the human endometrium throughout the menstrual cycle.". Hum. Reprod. 8 (9): 1420-5. PMID 8253928. 
  • Bertrand FE, Billips LG, Gartland GL, et al. (1996). "The J chain gene is transcribed during B and T lymphopoiesis in humans.". J. Immunol. 156 (11): 4240-4. PMID 8666793. 
  • Atkin JD, Pleass RJ, Owens RJ, Woof JM (1996). "Mutagenesis of the human IgA1 heavy chain tailpiece that prevents dimer assembly.". J. Immunol. 157 (1): 156-9. PMID 8683109. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
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