IGHE

From Wikipedia, the free encyclopedia

Immunoglobulin heavy constant epsilon

Identifiers

External IDs

Gene ontology
Molecular Function:	• antigen binding
Biological Process:	• immune response

Orthologs

Human

Mouse

Entrez

3497

n/a

Pubmed search

[1]

n/a

Immunoglobulin heavy constant epsilon, also known as IGHE, is a human gene.^[1]

[edit] References

^ Entrez Gene: IGHE immunoglobulin heavy constant epsilon.

[edit] Further reading

Venkitaraman AR, Williams GT, Dariavach P, Neuberger MS (1991). "The B-cell antigen receptor of the five immunoglobulin classes.". Nature 352 (6338): 777-81. doi:10.1038/352777a0. PMID 1881434.
Padlan EA, Davies DR (1987). "A model of the Fc of immunoglobulin E.". Mol. Immunol. 23 (10): 1063-75. PMID 3796618.
Flanagan JG, Rabbitts TH (1984). "The sequence of a human immunoglobulin epsilon heavy chain constant region gene, and evidence for three non-allelic genes.". EMBO J. 1 (5): 655-60. PMID 6234164.
Max EE, Battey J, Ney R, et al. (1982). "Duplication and deletion in the human immunoglobulin epsilon genes.". Cell 29 (2): 691-9. PMID 6288268.
Ellison J, Buxbaum J, Hood L (1983). "Nucleotide sequence of a human immunoglobulin C gamma 4 gene.". DNA 1 (1): 11-8. PMID 6299662.
Seno M, Kurokawa T, Ono Y, et al. (1983). "Molecular cloning and nucleotide sequencing of human immunoglobulin epsilon chain cDNA.". Nucleic Acids Res. 11 (3): 719-26. PMID 6300763.
Ueda S, Nakai S, Nishida Y, et al. (1984). "Long terminal repeat-like elements flank a human immunoglobulin epsilon pseudogene that lacks introns.". EMBO J. 1 (12): 1539-44. PMID 6327276.
Hisajima H, Nishida Y, Nakai S, et al. (1983). "Structure of the human immunoglobulin C epsilon 2 gene, a truncated pseudogene: implications for its evolutionary origin.". Proc. Natl. Acad. Sci. U.S.A. 80 (10): 2995-9. PMID 6407005.
Flanagan JG, Lefranc MP, Rabbitts TH (1984). "Mechanisms of divergence and convergence of the human immunoglobulin alpha 1 and alpha 2 constant region gene sequences.". Cell 36 (3): 681-8. PMID 6421489.
Ellison J, Hood L (1982). "Linkage and sequence homology of two human immunoglobulin gamma heavy chain constant region genes.". Proc. Natl. Acad. Sci. U.S.A. 79 (6): 1984-8. PMID 6804948.
Kenten JH, Molgaard HV, Houghton M, et al. (1983). "Cloning and sequence determination of the gene for the human immunoglobulin epsilon chain expressed in a myeloma cell line.". Proc. Natl. Acad. Sci. U.S.A. 79 (21): 6661-5. PMID 6815656.
Valenta R, Natter S, Seiberler S, et al. (1999). "Molecular characterization of an autoallergen, Hom s 1, identified by serum IgE from atopic dermatitis patients.". J. Invest. Dermatol. 111 (6): 1178-83. doi:10.1046/j.1523-1747.1998.00413.x. PMID 9856836.
Anderson GG, Leaves NI, Bhattacharyya S, et al. (2002). "Positive association to IgE levels and a physical map of the 13q14 atopy locus.". Eur. J. Hum. Genet. 10 (4): 266-70. doi:10.1038/sj.ejhg.5200801. PMID 12032735.
Cocco RR, Järvinen KM, Sampson HA, Beyer K (2003). "Mutational analysis of major, sequential IgE-binding epitopes in alpha s1-casein, a major cow's milk allergen.". J. Allergy Clin. Immunol. 112 (2): 433-7. PMID 12897753.
Hajoui O, Janani R, Tulic M, et al. (2004). "Synthesis of IL-13 by human B lymphocytes: regulation and role in IgE production.". J. Allergy Clin. Immunol. 114 (3): 657-63. doi:10.1016/j.jaci.2004.05.034. PMID 15356573.
Takhar P, Smurthwaite L, Coker HA, et al. (2005). "Allergen drives class switching to IgE in the nasal mucosa in allergic rhinitis.". J. Immunol. 174 (8): 5024-32. PMID 15814733.
Batra J, Rajpoot R, Ahluwalia J, et al. (2007). "A hexanucleotide repeat upstream of eotaxin gene promoter is associated with asthma, serum total IgE and plasma eotaxin levels.". J. Med. Genet. 44 (6): 397-403. doi:10.1136/jmg.2006.046607. PMID 17220216.