IFT57

From Wikipedia, the free encyclopedia

Intraflagellar transport 57 homolog (Chlamydomonas)

Identifiers

IFT57; ESRRBL1; FLJ10147; HIPPI; MHS4R2

External IDs

OMIM: 606621 MGI: 1921166 HomoloGene: 32383

Gene ontology
Molecular Function:	• protein binding
Cellular Component:	• flagellum
Biological Process:	• caspase activation • regulation of apoptosis

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_018010 (mRNA)
NP_060480 (protein)

NM_028680 (mRNA)
NP_082956 (protein)

Location

Chr 3: 109.36 - 109.42 Mb

Chr 16: 49.62 - 49.68 Mb

Pubmed search

[1]

[2]

Intraflagellar transport 57 homolog (Chlamydomonas), also known as IFT57, is a human gene.^[1]

[edit] References

^ Entrez Gene: IFT57 intraflagellar transport 57 homolog (Chlamydomonas).

[edit] Further reading

Gervais FG, Singaraja R, Xanthoudakis S, et al. (2002). "Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi.". Nat. Cell Biol. 4 (2): 95-105. doi:10.1038/ncb735. PMID 11788820.
Mattson MP (2002). "Accomplices to neuronal death.". Nature 415 (6870): 377-9. doi:10.1038/415377a. PMID 11807533.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Cheng CM, Huang SP, Chang YF, et al. (2003). "The viral death protein Apoptin interacts with Hippi, the protein interactor of Huntingtin-interacting protein 1.". Biochem. Biophys. Res. Commun. 305 (2): 359-64. PMID 12745083.
Baker SA, Freeman K, Luby-Phelps K, et al. (2003). "IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia.". J. Biol. Chem. 278 (36): 34211-8. doi:10.1074/jbc.M300156200. PMID 12821668.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Fan Y, Esmail MA, Ansley SJ, et al. (2004). "Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome.". Nat. Genet. 36 (9): 989-93. doi:10.1038/ng1414. PMID 15314642.
Majumder P, Chattopadhyay B, Mazumder A, et al. (2006). "Induction of apoptosis in cells expressing exogenous Hippi, a molecular partner of huntingtin-interacting protein Hip1.". Neurobiol. Dis. 22 (2): 242-56. doi:10.1016/j.nbd.2005.11.003. PMID 16364650.
Banerjee M, Majumder P, Bhattacharyya NP, et al. (2006). "Cloning, expression, purification, crystallization and preliminary crystallographic analysis of pseudo death-effector domain of HIPPI, a molecular partner of Huntingtin-interacting protein HIP-1.". Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 62 (Pt 12): 1247-50. doi:10.1107/S1744309106046628. PMID 17142908.
Majumder P, Chattopadhyay B, Sukanya S, et al. (2007). "Interaction of HIPPI with putative promoter sequence of caspase-1 in vitro and in vivo.". Biochem. Biophys. Res. Commun. 353 (1): 80-5. doi:10.1016/j.bbrc.2006.11.138. PMID 17173859.