IFNA5

From Wikipedia, the free encyclopedia

Interferon, alpha 5

Identifiers

External IDs

OMIM: 147565 MGI: 107664 HomoloGene: 88659

Gene ontology
Molecular Function:	• hematopoietin/interferon-class (D200-domain) cytokine receptor binding
Cellular Component:	• extracellular region • extracellular space
Biological Process:	• defense response • response to virus

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_002169 (mRNA)
NP_002160 (protein)

NM_010504 (mRNA)
NP_034634 (protein)

Location

Chr 9: 21.29 - 21.3 Mb

Chr 4: 88.31 - 88.31 Mb

Pubmed search

[1]

[2]

Interferon, alpha 5, also known as IFNA5, is a human gene.^[1]

[edit] References

^ Entrez Gene: IFNA5 interferon, alpha 5.

[edit] Further reading

Olopade OI, Bohlander SK, Pomykala H, et al. (1992). "Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia.". Genomics 14 (2): 437-43. PMID 1385305.
Henco K, Brosius J, Fujisawa A, et al. (1985). "Structural relationship of human interferon alpha genes and pseudogenes.". J. Mol. Biol. 185 (2): 227-60. PMID 4057246.
Goeddel DV, Leung DW, Dull TJ, et al. (1981). "The structure of eight distinct cloned human leukocyte interferon cDNAs.". Nature 290 (5801): 20-6. PMID 6163083.
Tiefenbrun N, Melamed D, Levy N, et al. (1996). "Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest.". Mol. Cell. Biol. 16 (7): 3934-44. PMID 8668211.
Chuntharapai A, Gibbs V, Lu J, et al. (1999). "Determination of residues involved in ligand binding and signal transmission in the human IFN-alpha receptor 2.". J. Immunol. 163 (2): 766-73. PMID 10395669.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9.". Nature 429 (6990): 369-74. doi:10.1038/nature02465. PMID 15164053.
Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites.". Protein Sci. 13 (10): 2819-24. doi:10.1110/ps.04682504. PMID 15340161.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.