IFNA10

From Wikipedia, the free encyclopedia

Interferon, alpha 10

Identifiers

IFNA10; MGC119878; MGC119879

External IDs

OMIM: 147577 MGI: 2667155 HomoloGene: 86885

Gene ontology
Molecular Function:	• interferon-alpha/beta receptor binding
Cellular Component:	• extracellular region • extracellular space
Biological Process:	• defense response • response to virus

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_002171 (mRNA)
NP_002162 (protein)

NM_177347 (mRNA)
NP_796321 (protein)

Location

Chr 9: 21.2 - 21.2 Mb

Chr 4: 88.12 - 88.12 Mb

Pubmed search

[1]

[2]

Interferon, alpha 10, also known as IFNA10, is a human gene.^[1]

[edit] References

^ Entrez Gene: IFNA10 interferon, alpha 10.

[edit] Further reading

Olopade OI, Bohlander SK, Pomykala H, et al. (1992). "Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia.". Genomics 14 (2): 437–43. PMID 1385305.
Bartholomew C, Windass JD (1989). "Identification of a functional allele of a human interferon-alpha gene previously characterized as a pseudogene.". J. Interferon Res. 9 (4): 407–17. PMID 2526839.
Henco K, Brosius J, Fujisawa A, et al. (1985). "Structural relationship of human interferon alpha genes and pseudogenes.". J. Mol. Biol. 185 (2): 227–60. PMID 4057246.
Goeddel DV, Leung DW, Dull TJ, et al. (1981). "The structure of eight distinct cloned human leukocyte interferon cDNAs.". Nature 290 (5801): 20–6. PMID 6163083.
Ullrich A, Gray A, Goeddel DV, Dull TJ (1982). "Nucleotide sequence of a portion of human chromosome 9 containing a leukocyte interferon gene cluster.". J. Mol. Biol. 156 (3): 467–86. PMID 6181262.
Fuke M, Hendrix LC, Bollon AP (1985). "Pseudogene IFN-alpha L: removal of the stop codon in the signal sequence permits expression of active human interferon.". Gene 32 (1-2): 135–40. PMID 6397400.
Tiefenbrun N, Melamed D, Levy N, et al. (1996). "Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest.". Mol. Cell. Biol. 16 (7): 3934–44. PMID 8668211.
Nyman TA, Tölö H, Parkkinen J, Kalkkinen N (1998). "Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes.". Biochem. J. 329 ( Pt 2): 295–302. PMID 9425112.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.