Talk:IC50

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[edit] IC50 - important concept - flawed definition

I'm not sure how wikipedia works, but this definition is so poorly done that it warrants being strongly edited or pulled. Minimally, it should be a one line (simple) definition, with cross-reference/citation to the work of an authority in this area. More than that, the person writing should be an expert. Prof D

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Improved the article to be more helpful. Moved most arcane paragraph to the end. I think this does its job now, alhtough it could certainly be improved/expanded...Teloscientist 21:20, 31 March 2007 (UTC)

[edit] Info about Inhibitors

I removed information in the lead paragraph relating to inhibitors.

"An inhibitor is a small molecule that lowers enzyme activity. In general, the higher the concentration of inhibitor, the more will enzyme activity be lowered. At any given concentration, two different inhibitors will have a different effect on the activity of the same enzyme. It is thus necessary to have a number which can be used to compare the potencies (i.e., how much a certain molecule will lower enzyme activity)."

This article is about IC50 which is a pharmacolgical constant. Inhibitors have IC50 values so I tried to reintegrate it with information already present in the article. I think that including it in the lead paragraph would mislead people into thinking it was a discussion about inhibitors not The IC50 concept Lilypink 19:04, 5 November 2007 (UTC)