Talk:Hyperthyroidism

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Should treatment discussion be on pages more specific to complaint?

Whilst most hyperthyroidism is easily treated, there are conditions that cause hyperthyroidism that are less easy to treat. Or as the advice one thyroid charity gives its telephone advisers 'avoid saying "it'll be alright" as sometimes it isn't'.

Contents 1 Radioiodine and Surgery treatment 2 In animals 3 "hyperthoxemia"? 4 Other symptoms 5 T3 & T4 6 Natural treatments? 7 Thyroid Storm Treatment 8 Hashimoto's Thyroiditis 9 PBDEs & hyperthryoidism in cats

[edit] Radioiodine and Surgery treatment

The text concerning the above comes in part from MediPrimer:Hyperthyroidism. As the copyright holder of that website, I authorize the use of this text under the GFDL as part of Wikipedia. Yashka78 00:11, 23 Jun 2005 (UTC)

[edit] In animals

Surgery is an option in feline hyperthyroidism, although it carries with it a number of risks. Radioiodine treatment is usually curative, while medication with methimazole may be used to control symptoms. All of these treatment options have advantages and disadvantages, so it is important to consider these and discuss them with a veterinarian.

[edit] "hyperthoxemia"?

What does this word mean? It's in the opening paragraph, but it doesn't google out. Google suggests "hyperthyroxemia", but that's not much better, with only 60 hits on google. Pubmed didn't have any hits for either, but suggested "hyperoxemia" for the first word and "hyperthyroxinemia" for the second one. If somebody knows what the author was going for, please fix it, but otherwise we might need to take the sentence out.--Arcadian 01:56, 30 November 2005 (UTC)

• hyperthyroxinemia - fixed. --Hugh2414 09:34, 30 November 2005 (UTC)
  • Thanks for the quick response and fix. --Arcadian 15:49, 30 November 2005 (UTC)

[edit] Other symptoms

Sorry. It may just be me, but isn't eye bulging a sign of hyperthroidism?

No, not necessarily. It may occur in Graves' disease, a common (but not the only) cause of hyperthyroidism. Isolated toxic nodules and a toxic nodular struma are not typically characterised by eye bulging. The eye bulging is due to the presence of TSH receptors on the retraorbital musculature, which are stimulated by the antibody. JFW | T@lk 21:54, 30 April 2006 (UTC)

[edit] T3 & T4

I noticed the article says hyperthyroidism can be caused by an excess or either T3 or T4 or both. Are the symptoms any different depending on which? 69.85.180.128 11:04, 3 February 2007 (UTC)

No, unless they are being caused by overose on pills. Then the T3 symptoms go away faster when the pills are stopped, due to its shorter half-life. SBHarris 15:15, 3 February 2007 (UTC)

[edit] Natural treatments?

Does anyone know of any supposed natural treatments, like with herbs or exercises? --Remi0o 03:27, 24 March 2007 (UTC)

Unlikely - the FDA would put a stop to that quickly... [[TheAngriestPharmacist]] 09:30, 3 May 2007 (UTC)

[edit] Thyroid Storm Treatment

• Propylthiouracil 900–1200 mg/day orally in four or six divided doses
• Methimazole 90–120 mg/day orally in four or six divided doses

• Sodium iodide Up to 2 g/day IV in single or divided doses
• Lugol’s solution 5–10 drops three times a day in water or juice
• Saturated solution of KI 1–2 drops three times a day in water or juice

• Propranolol 40–80 mg every 6 h

• Dexamethasone 5–20 mg/day orally or IV in divided doses
• Prednisone 25–100 mg/day orally in divided doses
• Methylprednisolone 20–80 mg/day IV in divided doses
• Hydrocortisone 100–400 mg/day IV in divided doses

[[TheAngriestPharmacist]] 09:29, 3 May 2007 (UTC)

2 issues - firstly, you should mention that the iodine based compounds ought to be given 1 to 4 hours after propylthiouracil (PTU). PTU is also the drug of choice for storm because of its effect on reducing T4 to T3 conversion. secondly i note that the main article states that TSH is the marker used in detecting hyperthyroidism - however there are certain conditions in which TSH is elevated (e.g. TSHoma) or unreliable (e.g. pregnancy) -- Unsigned

Sometimes though, TSH is all that can be used in detecting underlying thyroid issues as is

the case in subclinical hyper(or hypo)thyroidism. [[TheAngriestPharmacist]] 03:49, 6 May 2007 (UTC)

[edit] Hashimoto's Thyroiditis

Hashimoto's Thyroiditis is listed as the forth major cause of hyperthyroidism in this article but looking at the Hashimoto's article that it links to it is clear that it is a cause of HYPO thyroidism as it is a result of the autoimmune system attacking the thyroid gland.

Would someone care to clarify/fix/comment on this issue? Sail.not.swim (talk) 23:53, 18 November 2007 (UTC)

Hashimoto's thyroiditis is autoimmune inflamation and destruction of the thyroid gland as opposed to graves disease, in which auto antibodys mimick TSH to stimulate the thyroid.

In hashimoto's the initial inflamation of the gland causes release of T₃ and T₄ leaving the person transiently hyperthroid which is often sub clinical. As more and more and more of the gland is inflamed, damaged and destroyed its capability to produce T₃ and T₄ is compromised and the transient hyperthyroidism gives way to hypothyroidism, the more common clinical presentation of hashimoto's. —Preceding unsigned comment added by 80.235.131.226 (talk) 20:44, 1 April 2008 (UTC)

[edit] PBDEs & hyperthryoidism in cats

This subject has been given undue prominence - the 2007 article which proposed a link between PBDE and hyperthyroidism in cats ([1]) showed that the level of PBDEs in cats with hyperthyroidism was not significantly higher than the levels in other groups of cats, giving no evidence that PBDEs were responsible for the increase in hyperthyroidism in pet cats. A good discussion of the original Dye article was printed in the letters to the Veterinary Record: (letter from Kerry Simpson and the Feline Advisory Bureau feline expert panel [2])

Alternative suggested causes of the increased incidence of feline hyperthyroidism have been proposed over time - I would suggest these should be included in any discussion, although nothing has been proven to be a cause, otherwise hyperthyroidism in cats would be preventable... Murphyetta (talk) 14:05, 16 March 2008 (UTC)