Hypostatic gene

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A hypostatic gene is one whose phenotype is masked by the expression of an allele at a separate locus, in an epistasis event.

Example: In labrador retrievers, the chocolate coat colour is a result of homozygosity for a gene that is epistatic to the "black vs. yellow" gene. The alleles determining whether the dog is yellow or black, are that of the hypostatic gene in this event.

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[edit] Further Reading

Hartwell, Leland; L. Hood, M. Goldberg, A. Reynolds, L. Silver, R. Veres (2004). Genetics: From Genes to Genomes. New York, NY: McGraw-Hill, 56-57. ISBN 0-07-246248-5.