Hydroxylamine reductase

From Wikipedia, the free encyclopedia

In enzymology, a hydroxylamine reductase (EC 1.7.99.1) is an enzyme that catalyzes the chemical reaction

NH₃ + H₂O + acceptor hydroxylamine + reduced acceptor

The 3 substrates of this enzyme are NH₃, H₂O, and acceptor, whereas its two products are hydroxylamine and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with other acceptors. The systematic name of this enzyme class is ammonia:acceptor oxidoreductase. Other names in common use include hydroxylamine (acceptor) reductase, and ammonia:(acceptor) oxidoreductase. This enzyme participates in nitrogen metabolism. It has 2 cofactors: FAD, and Flavoprotein.

[edit] References

• IUBMB entry for 1.7.99.1
• BRENDA references for 1.7.99.1 (Recommended.)
• PubMed references for 1.7.99.1
• PubMed Central references for 1.7.99.1
• Google Scholar references for 1.7.99.1
• Taniguchi H, Mitsui H, Nakamura K and Egami F. "Ann. Acad. Sci. Fenn. Ser. A II 60 (1955) 200". 
• Walker GC and Nicholas DJD (1961). "Hydroxylamine reductase from Pseudomonas aeruginosa". Biochim. Biophys. Acta 49: 361–368. doi:10.1016/0006-3002(61)90135-4. 
• NJ, Ferguson SJ (2002). "Cytochrome cd1, reductive activation and kinetic analysis of a multifunctional respiratory enzyme". J. Biol. Chem. 277: 3093–100. doi:10.1074/jbc.M108944200. PMID 11709555. 

[edit] External links

The CAS registry number for this enzyme class is 37256-42-1.

• IUBMB entry for 1.7.99.1

• KEGG entry for 1.7.99.1

• BRENDA entry for 1.7.99.1

• NiceZyme view of 1.7.99.1

• EC2PDB: PDB structures for 1.7.99.1

• PRIAM entry for 1.7.99.1

• PUMA2 entry for 1.7.99.1

• IntEnz: Integrated Enzyme entry for 1.7.99.1

• MetaCyc entry for 1.7.99.1

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050418: hydroxylamine reductase

• AMIGO entry for GO code 0050418: hydroxylamine reductase