Hydroxydechloroatrazine ethylaminohydrolase

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In enzymology, a hydroxydechloroatrazine ethylaminohydrolase (EC 3.5.99.3) is an enzyme that catalyzes the chemical reaction

4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + H₂O N-isopropylammelide + ethylamine

Thus, the two substrates of this enzyme are 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine and H₂O, whereas its two products are N-isopropylammelide and ethylamine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in compounds that have not been otherwise categorized within EC number 3.5. The systematic name of this enzyme class is 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine ethylaminohydrolase. Other names in common use include AtzB, and hydroxyatrazine ethylaminohydrolase. This enzyme participates in atrazine degradation.

[edit] References

• IUBMB entry for 3.5.99.3
• BRENDA references for 3.5.99.3 (Recommended.)
• PubMed references for 3.5.99.3
• PubMed Central references for 3.5.99.3
• Google Scholar references for 3.5.99.3
• MJ (1997). "The atzB gene of Pseudomonas sp. strain ADP encodes the second enzyme of a novel atrazine degradation pathway". Appl. Environ. Microbiol. 63: 916–23. PMID 9055410. 

[edit] External links

• IUBMB entry for 3.5.99.3

• KEGG entry for 3.5.99.3

• BRENDA entry for 3.5.99.3

• NiceZyme view of 3.5.99.3

• EC2PDB: PDB structures for 3.5.99.3

• PRIAM entry for 3.5.99.3

• PUMA2 entry for 3.5.99.3

• IntEnz: Integrated Enzyme entry for 3.5.99.3

• MetaCyc entry for 3.5.99.3

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0018763: hydroxydechloroatrazine ethylaminohydrolase

• AMIGO entry for GO code 0018763: hydroxydechloroatrazine ethylaminohydrolase