Hydroxybutyrate-dimer hydrolase

From Wikipedia, the free encyclopedia

In enzymology, a hydroxybutyrate-dimer hydrolase (EC 3.1.1.22) is an enzyme that catalyzes the chemical reaction

(R)-3-((R)-3-hydroxybutanoyloxy)butanoate + H₂O 2 (R)-3-hydroxybutanoate

Thus, the two substrates of this enzyme are (R)-3-((R)-3-hydroxybutanoyloxy)butanoate and H₂O, whereas its product is (R)-3-hydroxybutanoate.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is (R)-3-((R)-3-hydroxybutanoyloxy)butanoate hydroxybutanoylhydrolase. This enzyme is also called D-(-)-3-hydroxybutyrate-dimer hydrolase. This enzyme participates in butanoate metabolism.

[edit] References

• IUBMB entry for 3.1.1.22
• BRENDA references for 3.1.1.22 (Recommended.)
• PubMed references for 3.1.1.22
• PubMed Central references for 3.1.1.22
• Google Scholar references for 3.1.1.22
• Delafield FP, Cooksey KE, Doudoroff M (1965). "beta-Hydroxybutyric dehydrogenase and dimer hydrolase of Pseudomonas lemoignei". J. Biol. Chem. 240: 4023–8. PMID 4954074. 

[edit] External links

The CAS registry number for this enzyme class is 37278-37-8.

• IUBMB entry for 3.1.1.22

• KEGG entry for 3.1.1.22

• BRENDA entry for 3.1.1.22

• NiceZyme view of 3.1.1.22

• EC2PDB: PDB structures for 3.1.1.22

• PRIAM entry for 3.1.1.22

• PUMA2 entry for 3.1.1.22

• IntEnz: Integrated Enzyme entry for 3.1.1.22

• MetaCyc entry for 3.1.1.22

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047989: hydroxybutyrate-dimer hydrolase

• AMIGO entry for GO code 0047989: hydroxybutyrate-dimer hydrolase