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A Hürthle cell (also known as Askanazy cell) is an oncocytic cell in the thyroid that is often associated with Hashimoto's thyroiditis as well as follicular thyroid cancer. Hürthle cells are characterized as enlarged epithelial cells with abundant eosinophilic granular cytoplasm as a result of altered mitochondria.[1] They generally stain pink and are prominently found in histological sections of thyroid glands affected with Hashimoto's.
A Hürthle cell adenoma is a well-differentiated type of follicular thyroid adenoma (benign tumor) that, in rare cases, has the potential to become malignant and metastasize (Hürthle cell carcinoma).
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