HRSP12

From Wikipedia, the free encyclopedia

Heat-responsive protein 12

PDB rendering based on 1oni.

Available structures: 1oni

Identifiers

Symbol(s)

HRSP12; PSP; P14.5; UK114

External IDs

OMIM: 602487 MGI: 1095401 HomoloGene: 4261

Gene ontology
Molecular Function:	• endonuclease activity • hydrolase activity
Cellular Component:	• nucleus • cytoplasm
Biological Process:	• regulation of translational termination

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_005836 (mRNA)
NP_005827 (protein)

NM_008287 (mRNA)
NP_032313 (protein)

Location

Chr 8: 99.18 - 99.2 Mb

Chr 15: 34.43 - 34.44 Mb

Pubmed search

[1]

[2]

Heat-responsive protein 12, also known as HRSP12, is a human gene.^[1]

[edit] References

^ Entrez Gene: HRSP12 heat-responsive protein 12.

[edit] Further reading

Mistiniene E, Pozdniakovaite N, Popendikyte V, Naktinis V (2006). "Structure-based ligand binding sites of protein p14.5, a member of protein family YER057c/YIL051c/YjgF.". Int. J. Biol. Macromol. 37 (1-2): 61–8. doi:10.1016/j.ijbiomac.2005.08.008. PMID 16198412.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Manjasetty BA, Delbrück H, Pham DT, et al. (2004). "Crystal structure of Homo sapiens protein hp14.5.". Proteins 54 (4): 797–800. doi:10.1002/prot.10619. PMID 14997576.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Kanouchi H, Oka T, Asagi K, et al. (2000). "Expression and cellular distribution of perchloric acid-soluble protein is dependent on the cell-proliferating states of NRK-52E cells.". Cell. Mol. Life Sci. 57 (7): 1103–8. PMID 10961346.
Morishita R, Kawagoshi A, Sawasaki T, et al. (1999). "Ribonuclease activity of rat liver perchloric acid-soluble protein, a potent inhibitor of protein synthesis.". J. Biol. Chem. 274 (29): 20688–92. PMID 10400702.
Colombo I, Ceciliani F, Ronchi S, et al. (1998). "cDNA cloning and Escherichia coli expression of UK114 tumor antigen.". Biochim. Biophys. Acta 1442 (1): 49–59. PMID 9767104.
Racca S, Di Carlo F, Bartorelli A, et al. (1998). "Growth inhibition of DMBA-induced rat mammary carcinomas by UK 114.". Virchows Arch. 431 (5): 323–8. PMID 9463573.
Schmiedeknecht G, Büchler C, Schmitz G (1998). "A bidirectional promoter connects the p14.5 gene to the gene for RNase P and RNase MRP protein subunit hPOP1.". Biochem. Biophys. Res. Commun. 241 (1): 59–67. doi:10.1006/bbrc.1997.7772. PMID 9405234.
Schmiedeknecht G, Kerkhoff C, Orsó E, et al. (1997). "Isolation and characterization of a 14.5-kDa trichloroacetic-acid-soluble translational inhibitor protein from human monocytes that is upregulated upon cellular differentiation.". Eur. J. Biochem. 242 (2): 339–51. PMID 8973653.
Oka T, Tsuji H, Noda C, et al. (1996). "Isolation and characterization of a novel perchloric acid-soluble protein inhibiting cell-free protein synthesis.". J. Biol. Chem. 270 (50): 30060–7. PMID 8530410.