HRC (gene)

From Wikipedia, the free encyclopedia


Histidine rich calcium binding protein
Identifiers
Symbol(s) HRC; MGC133236
External IDs OMIM: 142705 MGI: 96226 HomoloGene: 1622
Orthologs
Human Mouse
Entrez 3270 15464
Ensembl ENSG00000130528 ENSMUSG00000038239
Uniprot P23327 n/a
Refseq NM_002152 (mRNA)
NP_002143 (protein)		 NM_010473 (mRNA)
NP_034603 (protein)
Location Chr 19: 54.35 - 54.35 Mb Chr 7: 45.2 - 45.21 Mb
Pubmed search [1] [2]

Histidine rich calcium binding protein, also known as HRC, is a human gene.[1]

Histidine-rich calcium-binding protein is a luminal sarcoplasmic reticulum protein of 165 kD identified by its ability to bind low-density lipoprotein with high affinity[1]

[edit] References

  1. ^ a b Entrez Gene: HRC histidine rich calcium binding protein.

[edit] Further reading

  • Anderson NL, Anderson NG (2003). "The human plasma proteome: history, character, and diagnostic prospects.". Mol. Cell Proteomics 1 (11): 845–67. PMID 12488461. 
  • Hofmann SL, Topham M, Hsieh CL, Francke U (1991). "cDNA and genomic cloning of HRC, a human sarcoplasmic reticulum protein, and localization of the gene to human chromosome 19 and mouse chromosome 7.". Genomics 9 (4): 656–69. PMID 2037293. 
  • Hofmann SL, Brown MS, Lee E, et al. (1989). "Purification of a sarcoplasmic reticulum protein that binds Ca2+ and plasma lipoproteins.". J. Biol. Chem. 264 (14): 8260–70. PMID 2498310. 
  • Ridgeway AG, Petropoulos H, Siu A, et al. (1999). "Cloning, tissue distribution, subcellular localization and overexpression of murine histidine-rich Ca2+ binding protein.". FEBS Lett. 456 (3): 399–402. PMID 10462052. 
  • Lee HG, Kang H, Kim DH, Park WJ (2001). "Interaction of HRC (histidine-rich Ca(2+)-binding protein) and triadin in the lumen of sarcoplasmic reticulum.". J. Biol. Chem. 276 (43): 39533–8. doi:10.1074/jbc.M010664200. PMID 11504710. 
  • Sacchetto R, Damiani E, Turcato F, et al. (2002). "Ca(2+)-dependent interaction of triadin with histidine-rich Ca(2+)-binding protein carboxyl-terminal region.". Biochem. Biophys. Res. Commun. 289 (5): 1125–34. doi:10.1006/bbrc.2001.6126. PMID 11741309. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Kim E, Shin DW, Hong CS, et al. (2003). "Increased Ca2+ storage capacity in the sarcoplasmic reticulum by overexpression of HRC (histidine-rich Ca2+ binding protein).". Biochem. Biophys. Res. Commun. 300 (1): 192–6. PMID 12480542. 
  • Adkins JN, Varnum SM, Auberry KJ, et al. (2003). "Toward a human blood serum proteome: analysis by multidimensional separation coupled with mass spectrometry.". Mol. Cell Proteomics 1 (12): 947–55. PMID 12543931. 
  • Anderson JP, Dodou E, Heidt AB, et al. (2004). "HRC is a direct transcriptional target of MEF2 during cardiac, skeletal, and arterial smooth muscle development in vivo.". Mol. Cell. Biol. 24 (9): 3757–68. PMID 15082771. 
  • Fan GC, Gregory KN, Zhao W, et al. (2004). "Regulation of myocardial function by histidine-rich, calcium-binding protein.". Am. J. Physiol. Heart Circ. Physiol. 287 (4): H1705–11. doi:10.1152/ajpheart.01211.2003. PMID 15191886. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Arvanitis DA, Vafiadaki E, Fan GC, et al. (2007). "Histidine-rich Ca-binding protein interacts with sarcoplasmic reticulum Ca-ATPase.". Am. J. Physiol. Heart Circ. Physiol. 293 (3): H1581–9. doi:10.1152/ajpheart.00278.2007. PMID 17526652. 
 This article on a gene on chromosome 19 is a stub. You can help Wikipedia by expanding it.