HRASLS3

From Wikipedia, the free encyclopedia

HRAS-like suppressor 3

Identifiers

HRASLS3; H-REV107-1; HREV107; HREV107-3; MGC118754

External IDs

Gene ontology
Molecular Function:	• molecular_function
Cellular Component:	• cellular_component • membrane • integral to membrane
Biological Process:	• cell cycle • biological_process • negative regulation of progression through cell cycle

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_007069 (mRNA)
NP_009000 (protein)

NM_139269 (mRNA)
NP_644675 (protein)

Location

Chr 11: 63.1 - 63.14 Mb

Chr 19: 7.62 - 7.66 Mb

Pubmed search

[1]

[2]

HRAS-like suppressor 3, also known as HRASLS3, is a human gene.^[1]

[edit] References

^ Entrez Gene: HRASLS3 HRAS-like suppressor 3.

[edit] Further reading

Husmann K, Sers C, Fietze E, et al. (1998). "Transcriptional and translational downregulation of H-REV107, a class II tumour suppressor gene located on human chromosome 11q11-12.". Oncogene 17 (10): 1305-12. doi:10.1038/sj.onc.1202060. PMID 9771974.
Scanlan MJ, Gordan JD, Williamson B, et al. (1999). "Antigens recognized by autologous antibody in patients with renal-cell carcinoma.". Int. J. Cancer 83 (4): 456-64. PMID 10508479.
Siegrist S, Féral C, Chami M, et al. (2001). "hH-Rev107, a class II tumor suppressor gene, is expressed by post-meiotic testicular germ cells and CIS cells but not by human testicular germ cell tumors.". Oncogene 20 (37): 5155-63. doi:10.1038/sj.onc.1204658. PMID 11526504.
Sers C, Husmann K, Nazarenko I, et al. (2002). "The class II tumour suppressor gene H-REV107-1 is a target of interferon-regulatory factor-1 and is involved in IFNgamma-induced cell death in human ovarian carcinoma cells.". Oncogene 21 (18): 2829-39. doi:10.1038/sj.onc.1205377. PMID 11973642.
Roder K, Kim KH, Sul HS (2002). "Induction of murine H-rev107 gene expression by growth arrest and histone acetylation: involvement of an Sp1/Sp3-binding GC-box.". Biochem. Biophys. Res. Commun. 294 (1): 63-70. doi:10.1016/S0006-291X(02)00440-0. PMID 12054741.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell 125 (4): 801-14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
Nazarenko I, Kristiansen G, Fonfara S, et al. (2006). "H-REV107-1 stimulates growth in non-small cell lung carcinomas via the activation of mitogenic signaling.". Am. J. Pathol. 169 (4): 1427-39. PMID 17003497.
Nazarenko I, Schäfer R, Sers C (2007). "Mechanisms of the HRSL3 tumor suppressor function in ovarian carcinoma cells.". J. Cell. Sci. 120 (Pt 8): 1393-404. doi:10.1242/jcs.000018. PMID 17374643.