HPSE2

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Heparanase 2
Identifiers
Symbol(s) HPSE2; HPA2; HPR2; MGC133234
External IDs HomoloGene: 19680
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 60495 545291
Ensembl ENSG00000172987 n/a
Uniprot Q8WWQ2 n/a
Refseq NM_021828 (mRNA)
NP_068600 (protein)		 NM_001081257 (mRNA)
NP_001074726 (protein)
Location Chr 10: 100.21 - 100.99 Mb n/a
Pubmed search [1] [2]

Heparanase 2, also known as HPSE2, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: HPSE2 heparanase 2.

[edit] Further reading

  • D'Souza SS, Fazleabas AT, Banerjee P, et al. (2008). "Decidual heparanase activity is increased during pregnancy in the baboon (Papio anubis) and in in vitro decidualization of human stromal cells.". Biol. Reprod. 78 (2): 316-23. doi:10.1095/biolreprod.107.063891. PMID 17989358. 
  • Bar-Sela G, Kaplan-Cohen V, Ilan N, et al. (2006). "Heparanase expression in nasopharyngeal carcinoma inversely correlates with patient survival.". Histopathology 49 (2): 188-93. doi:10.1111/j.1365-2559.2006.02469.x. PMID 16879396. 
  • Beckhove P, Helmke BM, Ziouta Y, et al. (2005). "Heparanase expression at the invasion front of human head and neck cancers and correlation with poor prognosis.". Clin. Cancer Res. 11 (8): 2899-906. doi:10.1158/1078-0432.CCR-04-0664. PMID 15837740. 
  • Ogishima T, Shiina H, Breault JE, et al. (2005). "Increased heparanase expression is caused by promoter hypomethylation and up-regulation of transcriptional factor early growth response-1 in human prostate cancer.". Clin. Cancer Res. 11 (3): 1028-36. PMID 15709168. 
  • Wang Z, Xu H, Jiang L, et al. (2005). "Positive association of heparanase expression with tumor invasion and lymphatic metastasis in gastric carcinoma.". Mod. Pathol. 18 (2): 205-11. doi:10.1038/modpathol.3800282. PMID 15475937. 
  • Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10.". Nature 429 (6990): 375-81. doi:10.1038/nature02462. PMID 15164054. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • McKenzie E, Tyson K, Stamps A, et al. (2000). "Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member.". Biochem. Biophys. Res. Commun. 276 (3): 1170-7. doi:10.1006/bbrc.2000.3586. PMID 11027606. 
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