HMG20B

From Wikipedia, the free encyclopedia

High-mobility group 20B

PDB rendering based on 2crj.

Available structures: 2crj

Identifiers

Symbol(s)

HMG20B; BRAF25; BRAF35; FLJ26127; HMGX2; PP7706; SMARCE1r; SOXL; pp8857

External IDs

OMIM: 605535 MGI: 1341190 HomoloGene: 74949

Gene ontology
Molecular Function:	• transcription factor activity • aminoacyl-tRNA ligase activity • ATP binding
Cellular Component:	• chromatin • nucleus
Biological Process:	• transcription • regulation of transcription, DNA-dependent • tRNA aminoacylation for protein translation • cell cycle • chromatin modification

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_006339 (mRNA)
NP_006330 (protein)

NM_010440 (mRNA)
NP_034570 (protein)

Location

Chr 19: 3.52 - 3.53 Mb

Chr 10: 80.75 - 80.75 Mb

Pubmed search

[1]

[2]

High-mobility group 20B, also known as HMG20B, is a human gene.^[1]

[edit] References

^ Entrez Gene: HMG20B high-mobility group 20B.

[edit] Further reading

Wattler F, Wattler S, Kelly M, et al. (1999). "Cloning, chromosomal location, and expression analysis of murine Smarce1-related, a new member of the high-mobility 365 group gene family.". Genomics 60 (2): 172–8. doi:10.1006/geno.1999.5913. PMID 10486208.
Sumoy L, Carim L, Escarceller M, et al. (2000). "HMG20A and HMG20B map to human chromosomes 15q24 and 19p13.3 and constitute a distinct class of HMG-box genes with ubiquitous expression.". Cytogenet. Cell Genet. 88 (1-2): 62–7. PMID 10773667.
Marmorstein LY, Kinev AV, Chan GK, et al. (2001). "A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression.". Cell 104 (2): 247–57. PMID 11207365.
Lee YM, Shin H, Choi W, et al. (2002). "Characterization of human SMARCE1r high-mobility-group protein.". Biochim. Biophys. Acta 1574 (3): 269–76. PMID 11997092.
Hakimi MA, Bochar DA, Chenoweth J, et al. (2002). "A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes.". Proc. Natl. Acad. Sci. U.S.A. 99 (11): 7420–5. doi:10.1073/pnas.112008599. PMID 12032298.
Wang C, McCarty IM, Balazs L, et al. (2002). "Cloning a cDNA encoding an alternatively spliced protein of BRCA2-associated factor 35.". Biochem. Biophys. Res. Commun. 295 (1): 129–35. PMID 12083779.
Wang C, McCarty IM, Balazs L, et al. (2002). "Immunohistological detection of BRAF25 in human prostate tumor and cancer specimens.". Biochem. Biophys. Res. Commun. 295 (1): 136–41. PMID 12083780.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Hakimi MA, Dong Y, Lane WS, et al. (2003). "A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes.". J. Biol. Chem. 278 (9): 7234–9. doi:10.1074/jbc.M208992200. PMID 12493763.
Lee YM, Kim W (2003). "Association of human kinesin superfamily protein member 4 with BRCA2-associated factor 35.". Biochem. J. 374 (Pt 2): 497–503. doi:10.1042/BJ20030452. PMID 12809554.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19.". Nature 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824.
Iwase S, Januma A, Miyamoto K, et al. (2004). "Characterization of BHC80 in BRAF-HDAC complex, involved in neuron-specific gene repression.". Biochem. Biophys. Res. Commun. 322 (2): 601–8. doi:10.1016/j.bbrc.2004.07.163. PMID 15325272.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.