From Wikipedia, the free encyclopedia
HLA-B*82 (B*82) is an HLA-B allele-group. There is no current useful serotyping for HLA-B*82 gene products.[1] B*8201 was first identified by sequence analysis and appears to be derived by gene conversion between B*5602 and another HLA class I allele.[2], later B*8202 was identified in a caucasian and was suggested to be ancestral to B*8201, as product between gene conversion of B*5602 allele and B*4501 allele. B*82 is more common in East Africa, Kenya and Sudan, the frequency of B*8201 is found in the peoples to the west, sporadically in Central and West Africa, B*8202 is found in Sudan and Saudi Arabia.[3]
[edit] Serotype
B82 serotype recognition of Some HLA B*82 allele-group gene products[4]
| B*82 |
B82 |
other |
Sample |
| allele |
% |
% |
size (N) |
| 8201 |
3 |
79 |
146 |
[edit] Allele frequencies
[edit] References
- ^ Marsh SG, Albert ED, Bodmer WF, et al (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
- ^ Hurley CK, Steiner N, Hoyer RJ, et al (1996). "Novel HLA-B alleles, B*8201, B*3515 and B*5106, add to the complexity of serologic identification of HLA types". Tissue Antigens 47 (3): 179–87. PMID 8740766.
- ^ Cox ST, Hossain E, McWhinnie A, Prokupek B, Madrigal JA, Little AM (2000). "HLA-B*8202 identified in a Caucasoid potential bone marrow donor". Tissue Antigens 56 (2): 188–91. PMID 11019925.
- ^ derived from IMGT/HLA
- ^ a b c d e f g h i j Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens 61 (5): 403-7. PMID 12753660.
