HLA-B73

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major histocompatibility complex (human), class I, B73
Alleles B*7301
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*7301
Locus chr.6 6p21.31

HLA-B73 (B73) is an HLA-B serotype. The serotype identifies the HLA-B*7301 gene product.[1] Part of B*7301 is similar to the HLA-B22 family, however part resembles the domains seen in other apes.[2] B73 is more common in Western Indian Ocean, Mediterranean and Africa. (For terminology help see: HLA-serotype tutorial)

[edit] Serotype

B73 serotype recognition of B*7301 allele-group gene products[3]
B*73 B73 Other Sample
allele  %  % size (N)
7301 22 69 106


[edit] B*7301 frequencies

HLA B*7301 frequencies
freq
ref. Population (%)
[4] Parsi (Karachi, Pakistan) 4.9
[4] United Arab Emirates 2.0
[4] Italy 2.0
[4] Seri (Sonora, Mexico) 1.5
[4] P'urhépecha (Michoacan, Mexico) 1.5
[4] Jews (Israel) (*2 studies) 1.2
[4] Beti (Cameroon) 1.1
[4] Casablanca (Morocco) 0.9
[4] Tbilisi (Georgia) 0.9
[4] Mossi (Burkina Faso ) 0.9
[4] Bulgaria 0.9
[4] Sudanese 0.8
[4] Tuva (Russia) (2) 0.8
[4] Oman 0.8
[4] Bamileke (Cameroon) 0.6
[4] Pathan (Pakistan) 0.5
[4] Khalkha (Mongolia) 0.5
[4] Druse Arabs (Israel) 0.5
[4] Baloch (Iran) 0.5
[4] Manchester (England) 0.5
[4] Algeria (1) 0.5
[4] Turkey 0.4
[4] Amman (Jordan) 0.3
[4] Shona (Harare, Zimbabwe) 0.2
[4] Republic of Macedonia 0.2
[4] Nandi (Kenya) 0.2
[4] Luo (Kenya) 0.2
[4] Campania (Italy) 0.2
[4] Greece 0.2

[edit] References

  1. ^ Marsh SG, Albert ED, Bodmer WF, et al (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720. 
  2. ^ Hoffmann HJ, Kristensen TJ, Jensen TG, Graugaard B, Lamm LU (1995). "Antigenic characteristics and cDNA sequences of HLA-B73". Eur. J. Immunogenet. 22 (3): 231–40. PMID 8547229. 
  3. ^ derived from IMGT/HLA
  4. ^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens 61 (5): 403–7. PMID 12753660. 
v • d • e
HLA-B serotypes and allele groups

HLA-B · B5 (B51 · B52) · B7 · B8 · B12 (B44 · B45) · B13 · B14 (B64 · B65) · B15 (B62 · B63 · B70 · B71 · B75 · B76 · B77) · B16 (B38 · B39) · B17 (B57 · B58) · B18 · B21 (B49 · B50) · B22 (B54 · B55 · B56) · B27 · B35 · B37 · B40 (B60 · B61) · B41 · B42 · B46 · B47 · B48 · B53 · B59 · B67 · B73 · B78 · B81 · B*82 · B*83