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HLA-B59 (B59) is an HLA-B serotype. The serotype identifies the more common HLA-B*## gene products.[1] B59 is a hybrid between B*55 and B*51.[2] B59 is more common in Japan, Korea, N. China and Mongolia. (For terminology help see: HLA-serotype tutorial)
[edit] Serotype
B59 serotype recognition of the HLA B*59 allele-group gene products[3]
| B*59 |
B59 |
Other |
Sample |
| allele |
% |
% |
size (N) |
| 5901 |
45 |
41 |
123 |
[edit] B*5901 allele frequencies
HLA B*5901 frequencies
|
|
freq |
| ref. |
Population |
(%) |
| [4] |
Okinawan (USA Hawaii) |
6.3 |
| [4] |
Japan (2) |
2.7 |
| [4] |
Tarialan Khoton (Mongolia) |
2.4 |
| [4] |
South Korea (3) |
2.1 |
| [4] |
Gipuscoa Basque (Spain) |
2.0 |
| [4] |
Japan Central |
1.8 |
| [4] |
Casablanca (Morocco) |
1.8 |
| [4] |
Hyogo (Japan) |
1.6 |
| [4] |
N. Korean (Harbin,China) |
1.0 |
| [4] |
Manchu (Harbin, China) |
0.6 |
| [4] |
Naxi (Yunnan, China) |
0.6 |
| [4] |
Girona (Catalonia,Spain) |
0.6 |
| [4] |
Algeria (1) |
0.5 |
| [4] |
Inner Mongolia (China) |
0.5 |
| [4] |
Khalkha (Mongolia) |
0.5 |
| [4] |
Shanghai (China) |
0.3 |
| [4] |
Essen (German ) |
0.3 |
| [4] |
Southern Han (China) |
0.2 |
| [4] |
Shij. Tian. (Beijing, China) |
0.1 |
| [4] |
Hakka (Taiwan) |
0.1 |
Regions of higher B*5901 frequency
| Japan |
 |
| Korea |
 |
| Mongolia |
 |
Heilongjiang
prov., China
(Harbin city) |
 |
[edit] References
- ^ Marsh SG, Albert ED, Bodmer WF, et al (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
- ^ Hildebrand WH, Domena JD, Parham P (1993). "Primary structure shows HLA-B59 to be a hybrid of HLA-B55 and HLA-B51, and not a subtype of HLA-B8". Tissue Antigens 41 (4): 190–5. PMID 8362411.
- ^ derived from IMGT/HLA
- ^ a b c d e f g h i j k l m n o p q r s t Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens 61 (5): 403–7. PMID 12753660.
