HLA-B56

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major histocompatibility complex (human), class I, B56
Alleles B*5601, *5602, *5603, *5604
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*5601
B*5602
B*5603
B*5604
Locus chr.6 6p21.31

HLA-B56 (B56) is an HLA-B serotype. B56 is a split antigen from the B22 broad antigen, sister serotypes are B54 and B55. The serotype identifies the more common HLA-B*56 gene products.[1] (For terminology help see: HLA-serotype tutorial)



[edit] Serotype

B56 and B22 serotype recognition of Some HLA B*56 allele-group gene products[2]
B*56 B56 B22 Sample
allele  %  % size (N)
5601 72 5 671
5603 46 8 13
5604 73 11


[edit] Allele distribution

HLA B*5601 frequencies
freq
ref. Population (%)
[3] Australian Aborigine Kimberly 35.5
[3] Papua New Guinea Madang 34.6
[3] Papua New Guinea New Britain Rabaul 31.6
[3] Taiwan Ami 20.4
[3] New Caledonia 19.2
[3] Australian Aborigine Groote Eylandt 18.0
[3] Australian Aborigine Cape York Peninsula 16.5
[3] Australian Aborigine Yuendumu 11.4
[3] China Yunnan Lisu 9.4
[3] China Yunnan Nu 3.8
[3] Senegal Niokholo Mandenka 2.7
[3] Sudanese 2.5
[3] American Samoa 2.0
[3] China Guangxi Maonan 1.9
[3] Taiwan Hakka 1.8
[3] Thailand 1.8
[3] Finland 1.7
[3] Georgia Tibilisi Kurds 1.7
[3] India Andhra Pradesh Golla 1.4
[3] Croatia 1.3
[3] Japan (5) 1.3
[3] South Africa Natal Tamil 1.0
[3] Taiwan Rukai 1.0

[edit] References

  1. ^ Marsh SG, Albert ED, Bodmer WF, et al (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720. 
  2. ^ derived from IMGT/HLA
  3. ^ a b c d e f g h i j k l m n o p q r s t u v w Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens 61 (5): 403–7. PMID 12753660. 
v • d • e
HLA-B serotypes and allele groups

HLA-B · B5 (B51 · B52) · B7 · B8 · B12 (B44 · B45) · B13 · B14 (B64 · B65) · B15 (B62 · B63 · B70 · B71 · B75 · B76 · B77) · B16 (B38 · B39) · B17 (B57 · B58) · B18 · B21 (B49 · B50) · B22 (B54 · B55 · B56) · B27 · B35 · B37 · B40 (B60 · B61) · B41 · B42 · B46 · B47 · B48 · B53 · B59 · B67 · B73 · B78 · B81 · B*82 · B*83