From Wikipedia, the free encyclopedia
HLA-A80 (A80) is the least common HLA-A group. The serotype identifies the more common HLA-A*8001 gene product. A80 is almost exclusively found in africa and recent immigrants groups from West Africa
[edit] Serotype
A80 and A10 serotype recognition of Some HLA A*3601 allele-group gene products[1]
A*80 |
A80 |
A10 |
Sample |
allele |
% |
% |
size (N) |
8001 |
36 |
10 |
505 |
HLA-A80 typing is poor. Most typing is done with SSP-PCR. Most of 8001 are detected with "Blank" serotype.
[edit] Distribution and References
HLA A*8001 frequencies
|
|
freq |
ref. |
Population |
(%) |
[2] |
Bamileke (Cameroon) |
1.9 |
|
|
Botswana |
1.8 |
[3] |
Fulani (Burkino Faso) |
1.0 |
|
|
[2] |
Bete(Cameroon) |
0.6 |
|
|
Bubi(Eq. Guinea) |
0.5 |
|
- ^ derived from IMGT/HLA
- ^ a b Torimiro JN, Carr JK, Wolfe ND, et al (2006). "HLA class I diversity among rural rainforest inhabitants in Cameroon: identification of A*2612-B*4407 haplotype". Tissue Antigens 67 (1): 30–7. doi:10.1111/j.1399-0039.2005.00527.x. PMID 16451198.
- ^ Modiano D, Luoni G, Petrarca V, et al (2001). "HLA class I in three West African ethnic groups: genetic distances from sub-Saharan and Caucasoid populations". Tissue Antigens 57 (2): 128–37. PMID 11260507.