HLA-A30

From Wikipedia, the free encyclopedia

major histocompatibility complex (human), class I, A30
Alleles A*3001
A*3002
A*3003
A*3004
Structure (See HLA-A)
Identifiers
3001 3002 3003 3004
Symbol(s) HLA-A
EBI-HLA A*3001
EBI-HLA A*3002
EBI-HLA A*3003
EBI-HLA A*3004
Shared data
Locus chr.6 6p21.31

HLA-A30 (A30) is an HLA-A serotype. The serotype identifies the more common HLA-A*30 gene products. A30 is a split antigen of the A19 broad antigen serotype group. It is similar to the A29, A31, A32, A33, and A74 HLA antigens.

[edit] Serotype

A30 and A19 serotype recognition of Some HLA A*30 allele-group gene products[1]
A*30 A30 A19 Sample
allele  %  % size (N)
3001 89 1 2895
3002 93 1 2124
3003 67 6
3004 94 85


[edit] Disease association

A*3002 alters Type 1 diabetes risk[2]

[edit] References

  1. ^ derived from IMGT/HLA
  2. ^ Noble J, Valdes A, Bugawan T, Apple R, Thomson G, Erlich H (2002). "The HLA class I A locus affects susceptibility to type 1 diabetes.". Hum Immunol 63 (8): 657–64. doi:10.1016/S0198-8859(02)00421-4. PMID 12121673.