Talk:HIV disease progression rates

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You're doing a great job with cleanup. Keep it up, it could be shaved even more. Nice formatting too.

You might mention with Rapid Progressors that drug/alcohol abuse, especially amphetamines, activates latent cells that might otherwise be dormant for years. Also alcohol for instance, a drug that characteristically damages the liver over time already, will also be fighting against anti-retroviral treatments for metabolising priority thus rendering HAARTs less effective.

The newest "oh my lord there is an HIV strain that kills in 5 seconds" media coverage of the man in New York chronically abused methamphetamines. You could use sources from there. JoeSmack (talk) 17:31, August 10, 2005 (UTC)

P.S. I noticed viral strain varitability in the intro but not in RP/LNTP sections. Some strains attack faster, others slower. Important sentence for each I think. - whoops, this has it's own section, sorry.

P.P.S. I think you should use the AIDSinfo definition of LNTPs which is 7-12 years, not 12 years. JoeSmack (talk) 17:49, August 10, 2005 (UTC)

P.P.P.S. The technicalness of this article can make it pretty hard to read. Here is an example from the section on co-infections (hep G. has been shown to slow AIDS progression btw, in case you didn't know):

"Activated cells also release IFN-alpha which acts on an autocrine and paracrine loop that up-regulates the levels of physiologically active NF-kappa B which activates host cell genes as well as the HIV-1 LTR (Gaynor, 1992; Baeuerle, 1991)"

...thats like...wow...I don't even know. Technical cleanup is next step, I know you're working on it as you can though. JoeSmack (talk) 17:57, August 10, 2005 (UTC)

[edit] Opinion

This article's sections need to be split up into paragraphs. It's very hard to read, and it's also rather dry. Lots of good material, if you're a doctor :). njaard 06:44, 10 September 2007 (UTC)