Histidinol-phosphatase

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In enzymology, a histidinol-phosphatase (EC 3.1.3.15) is an enzyme that catalyzes the chemical reaction

L-histidinol phosphate + H2O \rightleftharpoons L-histidinol + phosphate

Thus, the two substrates of this enzyme are L-histidinol phosphate and H2O, whereas its two products are L-histidinol and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is L-histidinol-phosphate phosphohydrolase. Other names in common use include histidinol phosphate phosphatase, L-histidinol phosphate phosphatase, histidinolphosphate phosphatase, HPpase, and histidinolphosphatase. This enzyme participates in histidine metabolism.

Contents

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[edit] Structural studies

As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes 2FPR, 2FPS, 2FPU, 2FPW, and 2FPX.

[edit] References

[edit] External links

The CAS registry number for this enzyme class is 9025-79-0.

[edit] Gene Ontology (GO) codes