Hexadecanal dehydrogenase (acylating)

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In enzymology, a hexadecanal dehydrogenase (acylating) (EC 1.2.1.42) is an enzyme that catalyzes the chemical reaction

hexadecanal + CoA + NAD⁺ hexadecanoyl-CoA + NADH + H⁺

The 3 substrates of this enzyme are hexadecanal, CoA, and NAD⁺, whereas its 3 products are hexadecanoyl-CoA, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is hexadecanal:NAD+ oxidoreductase (CoA-acylating). This enzyme is also called fatty acyl-CoA reductase.

[edit] References

• IUBMB entry for 1.2.1.42
• BRENDA references for 1.2.1.42 (Recommended.)
• PubMed references for 1.2.1.42
• PubMed Central references for 1.2.1.42
• Google Scholar references for 1.2.1.42
• Johnson RC, Gilbertson JR (1972). "Isolation, characterization, and partial purification of a fatty acyl coenzyme A reductase from bovine cardiac muscle". J. Biol. Chem. 247: 6991–8. PMID 4343165. 

[edit] External links

The CAS registry number for this enzyme class is 72561-01-4.

• IUBMB entry for 1.2.1.42

• KEGG entry for 1.2.1.42

• BRENDA entry for 1.2.1.42

• NiceZyme view of 1.2.1.42

• EC2PDB: PDB structures for 1.2.1.42

• PRIAM entry for 1.2.1.42

• PUMA2 entry for 1.2.1.42

• IntEnz: Integrated Enzyme entry for 1.2.1.42

• MetaCyc entry for 1.2.1.42

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047104: hexadecanal dehydrogenase (acylating)

• AMIGO entry for GO code 0047104: hexadecanal dehydrogenase (acylating)