Herpes B Virus

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B Virus( Cercopithecine herpesvirus 1, herpesvirus simiae, Herpes B virus) is the endemic simplex virus of macaques, in which the virus exhibits pathogenesis similar to that of herpes simplex virus in humans. Conversely, when humans are zoonotically infected with B virus, undiagnosed and untreated patients can present with severe CNS disease, resulting in permanent neurological dysfunction or death. It is estimated that the mortality rate for untreated patients is near 80%. The last known fatality occurred when a worker at the Yerkes National Primate Research Center was infected in 1997. Proper personal protective equipment is essential when working with macaque monkeys, especially those who have tested positive for the virus. Bites, scratches, and exposures to mucous membranes, including the eye, must be cleansed immediately and samples from the macaque and human should be sent for B virus diagnostic testing as recommended by the B Virus Working Group here: BVIRUS.pdf

As of 1992, there had been approximately 25 reported cases of Herpes B of which 16 patients died, and at least 20 developed encephalitis.^[1][2]

[edit] External links

• B Virus Resource Laboratory
• CDC/NCID B Virus Page
• Herpes B virus — "B" is for Brebner: Dr. William Bartlet Brebner (1903–1932)

[edit] Footnotes