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| Hepatitis C virus (HCV) cis-acting replication element (CRE) |
 |
| Type: |
Cis-reg; |
| 2° structure: |
Published; PubMed |
| Seed alignment: |
PubMed |
| Avg length: |
51.0 nucleotides |
| Avg identity: |
87% |
|
The Hepatitis C virus (HCV) cis-acting replication element (CRE) is an RNA element which is found in the coding region of the RNA-dependent RNA polymerase NS5B. Mutations in this family have been found to cause a blockage in RNA replication and it is thought that both the primary sequence and the structure of this element are crucial for HCV RNA replication.[1]
[edit] References
- ^ You, S; Stump DD, Branch AD, Rice CM (2004). "A cis-acting replication element in the sequence encoding the NS5B RNA-dependent RNA polymerase is required for hepatitis C virus RNA replication". J Virol 78: 1352–1366. doi:10.1128/JVI.78.3.1352-1366.2004. PMID 14722290.
[edit] External links
