Henry Drysdale Dakin

From Wikipedia, the free encyclopedia

Henry Drysdale Dakin
Born	March 12 1880 London, England
Died	February 10, 1952 (aged 71) Scarsdale, New York, USA
Residence	England
Nationality	English
Institutions	University of Leeds, University of Heidelberg, Columbia University
Alma mater	University of Leeds
Doctoral advisor	Julius B. Cohen, Albrecht Kossel
Known for	Carrel-Dakin method, Dakin reaction, Dakin-West reaction

Henry Drysdale Dakin (1880 - 1952) was an English chemist.

He was born in London as the youngest of 8 children to a family of steel merchants from Leeds. As a school boy he did water analysis with the Leeds City Analyst. He studied chemistry at the University of Leeds with Julius B. Cohen and after he worked with Albrecht Kossel on arginase at the University of Heidelberg he joint Columbia University in 1905, working in the lab of Christian Herter. During his work on amino acids he obtained his PhD from Leeds. In 1914 he went back to England to offer his service with the war effort. Due to a request for a chemist by Alexis Carrel to the Rockefeller Institute, Dakin joined Carrel in 1916 at a temporary hospital in Compiègne. There they developed the Carrel-Dakin method of wound treatments. This consisted of intermittently irrigating the wound with Dakin's solution. This solution is a highly diluted antiseptic, consisting of sodium hypochlorite (0.4% to 0.5%) and boric acid (4%). It is unstable and deteriorates within a few days, and must be made as needed. Since 1982 a modified, more stable Dakin's Solution has been commercially available from Century Pharmaceuticals, Inc. After he married the widow of Christian Herter in 1916, he worked in his private laboratory in Scarsdale, New York and had several close collaborations with other scientists. His main working fields where amino acids and enzymes. The extraction of amino acids from hydrolyzed peptides by butanol was invented by him. He also was interested in organic chemistry and synthesis yielding the Dakin reaction and the Dakin-West reaction.

He died shortly after the death of his wife in early 1952.

[edit] Reference

Percival Hartley (1952). "Henry Drysdale Dakin. 1880-1952". Obituary Notices of Fellows of the Royal Society 8 (21): 128–148. doi:10.1098/rsbm.1952.0009.
C. Rezayat, W. Widmann, M. Hardy (1952). "Henry Drysdale Dakin: More Than His Solution". Current Surgery 63 (3): 194–196. doi:10.1016/j.cursur.2006.04.009.