Heme-transporting ATPase

From Wikipedia, the free encyclopedia

In enzymology, a heme-transporting ATPase (EC 3.6.3.41) is an enzyme that catalyzes the chemical reaction

ATP + H₂O + hemein ADP + phosphate + hemeout

The 3 substrates of this enzyme are ATP, H₂O, and heme, whereas its 3 products are ADP, phosphate, and heme.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (heme-exporting). This enzyme participates in abc transporters - general.

[edit] References

• IUBMB entry for 3.6.3.41
• BRENDA references for 3.6.3.41 (Recommended.)
• PubMed references for 3.6.3.41
• PubMed Central references for 3.6.3.41
• Google Scholar references for 3.6.3.41
• Saier MH Jr (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol. 40: 81–136. PMID 9889977. 
• Jekabsons W, Schuster W (1995). "orf250 encodes a second subunit of an ABC-type heme transporter in Oenothera mitochondria". Mol. Gen. Genet. 246: 166–73. doi:10.1007/BF00294679. PMID 7862087. 
• Ramseier TM, Winteler HV, Hennecke H (1991). "Discovery and sequence analysis of bacterial genes involved in the biogenesis of c-type cytochromes". J. Biol. Chem. 266: 7793–803. PMID 1850420. 

[edit] External links

• IUBMB entry for 3.6.3.41

• KEGG entry for 3.6.3.41

• BRENDA entry for 3.6.3.41

• NiceZyme view of 3.6.3.41

• EC2PDB: PDB structures for 3.6.3.41

• PRIAM entry for 3.6.3.41

• PUMA2 entry for 3.6.3.41

• IntEnz: Integrated Enzyme entry for 3.6.3.41

• MetaCyc entry for 3.6.3.41

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0015439: heme-transporting ATPase

• AMIGO entry for GO code 0015439: heme-transporting ATPase